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About This Item
Empirical Formula (Hill Notation):
C10H15N5O10P2 · xNa+
CAS Number:
Molecular Weight:
427.20 (free acid basis)
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
MDL number:
Assay:
≥90% (HPLC)
Form:
powder
Solubility:
water: 50 mg/mL, clear, colorless
Storage temp.:
−20°C
Product Name
2′-Deoxyguanosine 5′-diphosphate sodium salt, ≥90% (HPLC)
Quality Segment
assay
≥90% (HPLC)
form
powder
solubility
water: 50 mg/mL, clear, colorless
storage temp.
−20°C
SMILES string
[Na].NC1=NC(=O)c2ncn(C3CC(O)C(COP(O)(=O)OP(O)(O)=O)O3)c2N1
InChI
1S/C10H15N5O10P2.Na.H/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(24-6)2-23-27(21,22)25-26(18,19)20;;/h3-6,16H,1-2H2,(H,21,22)(H2,18,19,20)(H3,11,13,14,17);;
InChI key
VLWIICGGBFZYEZ-UHFFFAOYSA-N
General description
2′-Deoxyguanosine 5′-diphosphate (dGDP) is a nucleotide with guanine base, deoxyribose and two phosphate.
Application
2′-Deoxyguanosine 5′-diphosphate (dGDP) is used as a substrate of dGDP (nucleoside diphosphate) kinase (2.7.4.6) or pyruvate kinase to produce dGTP in support of DNA biosynthesis. dGDP is used as a substrate to study the kinetics of glycoprotein (gp) 1.7 expressed by bacteriophage T7.
2′-Deoxyguanosine 5′-diphosphate sodium salt has been used as a xanthosine 5′-monophosphate analog and xanthine phosphoribosyl transferase inhibitor in kinetic studies.
Biochem/physiol Actions
2′-Deoxyguanosine 5′-diphosphate (dGDP) inhibits xanthine phosphoribosyl transferase (XPRT) and hypoxanthine-guanine phosphoribosyl transferase (HGPRT).
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| D9250-25MG | 04061833590508 |
| D9250-100MG | 04061833007013 |
