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Merck
CN

D9567

Anti-Dopamine Transporter, C-Terminus antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-DAT

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About This Item

UNSPSC Code:
12352203
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC (p), WB
Citations:
3
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

monkey, human

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, western blot: 1:1,000 using SDS-solubilized human striatal samples

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... SLC6A3(6531)

General description

The dopamine transporter (DAT1) acts to take released dopamine back up into presynaptic terminals and has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse.

Immunogen

synthetic peptide from the intracellular C-terminal region of human dopamine transporter.

Application

Anti-Dopamine Transporter, C-Terminus antibody produced in rabbit is suitable at a working dilution of 1:1000 for western blotting using SDS-solubilized human striatal samples and for immunohistochemistry using formaldehyde-fixed human and monkey brain sections.

Biochem/physiol Actions

The dopamine transporter (DAT1) acts to take released dopamine back up into presynaptic terminals and has been implicated in human disorders such as parkinsonism, Tourette syndrome, and substance abuse. DAT1 gene is a primary target gene for ADHD (Attention deficit hyperactivity disorder). DAT polymorphism along with maternal prenatal smoking is associated with childhood hyperactivity-impulsivity and inattentiveness.

Physical form

Solution in 10 mM HEPES, pH 7.5, 150 mM NaCl, 100 μg/mL BSA, and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)



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