D9570
Dothiepin hydrochloride
≥98% (HPLC)
Synonym(s):
3-Dibenzo[b,e]thepin-11(6H)-ylidine-N,N-dimethyl-1-propanamine hydrochloride
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C19H21NS·HCl
CAS Number:
Molecular Weight:
331.90
UNSPSC Code:
12352200
EC Number:
212-978-8
InChI key
XUPZAARQDNSRJB-CULRIWENSA-N
InChI
1S/C19H21NS.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H/b17-11-;
assay
≥98% (HPLC)
form
solid
solubility
DMSO: ≥26 mg/mL
storage temp.
room temp
Biochem/physiol Actions
Dothiepin hydrochloride is a tricyclic antidepressant.
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
C Amey
Journal of affective disorders, 125(1-3), 111-115 (2010-06-24)
Antidepressant-induced switch to mania has not been thoroughly characterized in bipolar disorder and is even less well understood in unipolar depression. I describe, as a first-person narrative, my own experience of psychotic mania, which was suspected to have been induced
H S Kiran et al.
The Journal of the Association of Physicians of India, 58, 120-122 (2010-07-27)
Tricyclic antidepressants (TCAs) may have dangerous cardiac effects in overdose. ECG is useful as both a screening tool for tricyclic antidepressant exposure and as a prognostic indicator. TCA overdose may produce various ECG changes. We report a case of Dothiepin
Case of epirubicin-induced cardiomyopathy in familial cardiomyopathy.
Kate E Shipman et al.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 29(18), e537-e538 (2011-04-13)
Delirium as a symptom of tricyclic antidepressant withdrawal.
Jacob Alexander et al.
The Australian and New Zealand journal of psychiatry, 44(9), 863-863 (2010-09-08)
Peter Lepping et al.
Addiction (Abingdon, England), 102(7), 1166-1167 (2007-06-15)
Tricyclic antidepressants sometimes trigger mania in bipolar patients, but little is known about their potential for abuse in this regard. We describe a man with bipolar disorder and alcohol dependency who abused dosulepin repeatedly in order to induce manic episodes.
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service