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Merck
CN

D9641

Deoxygalactonojirimycin hydrochloride

powder or solid, ≥98% (HPLC)

Synonym(s):

1,5-Dideoxy-1,5-imino-D-galactitol, Migalastat

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About This Item

Empirical Formula (Hill Notation):
C6H13NO4 · HCl
CAS Number:
Molecular Weight:
199.63
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.32
MDL number:
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Product Name

Deoxygalactonojirimycin hydrochloride,

biological source

synthetic (organic)

Quality Segment

assay

≥98% (HPLC)

form

powder or solid

solubility

water: soluble 1 mg/mL

storage temp.

−20°C

SMILES string

Cl.OC[C@H]1NC[C@H](O)[C@@H](O)[C@H]1O

InChI

1S/C6H13NO4.ClH/c8-2-3-5(10)6(11)4(9)1-7-3;/h3-11H,1-2H2;1H/t3-,4+,5+,6-;/m1./s1

InChI key

ZJIHMALTJRDNQI-OLALXQGDSA-N

Application

Deoxygalactonojirimycin hydrochloride has been used as an α-galactosidase A inhibitor to assess the enzymatic activity of α-galactosidase A. It has also been used as an α-galactosidase A inhibitor to study its effects on the mRNA levels in human embryonic kidney (HEK) cells and hippocampal neurons.

Biochem/physiol Actions

Deoxygalactonojirimycin hydrochloride is an inhibitor of α-galactosidase A. Deoxygalactonojirimycin exhibits therapeutic effects against Fabry disease.


Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Global Trade Item Number

SKUGTIN
D9641-2MG04061833270639