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Merck
CN

D9885

Sigma-Aldrich

DEAE-Dextran hydrochloride

powder

Synonym(s):

Diethylaminoethyl-dextran hydrochloride

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About This Item

CAS Number:
9064-91-9
MDL number:
MFCD00081561
UNSPSC Code:
12352201
NACRES:
NA.25

Key Documents

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biological source

bacterial (Leuconostoc mesenteroides)

Quality Level

200

form

powder

extent of labeling

~3.2% nitrogen

useful pH range

4.0 - 6.0

solubility

H2O: soluble 100 mg/mL, clear, colorless to faintly yellow

storage temp.

room temp

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Application

DEAE-Dextran 500, a polycationic stabilizing molecule and transfection reagent, is used in the development of sustained release protein delivery and nucleic acid transfection systems. DEAE-Dextran 500 may be used for cell immobilization in biosensors.

Other Notes

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
BCCN9343
BCCN9342
BCCN9341
BCCN4109
BCCN3951

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DEAE-dextran transfection of mammalian cultured cells.
E T Schenborn et al.
Methods in molecular biology (Clifton, N.J.), 130, 147-153 (1999-12-10)
Anita Bogdanov et al.
Antimicrobial agents and chemotherapy, 58(1), 405-413 (2013-11-06)
Chlamydiae are obligate intracellular bacteria that propagate in the inclusion, a specific niche inside the host cell. The standard method for counting chlamydiae is immunofluorescent staining and manual counting of chlamydial inclusions. High- or medium-throughput estimation of the reduction in
Transfection using DEAE-dextran.
Selden RF.
Current Protocols in Immunology, 10, 10-10 (2001)
Nattamon Niyomdecha et al.
Heliyon, 6(6), e04050-e04050 (2020-06-13)
Niclosamide has been known to inhibit a number of pH-dependent viruses via the neutralization of endosomal acidic pH. It has also been shown to disrupt the mTORC1 signaling pathway. The replication of many viruses requires mTORC1 activation. Here, we investigated
Shingo Kikuchi et al.
International journal of pharmaceutics, 386(1-2), 149-155 (2009-11-20)
A multivariate statistical technique was applied to designing a tablet for the sustained release over 24h of diltiazem hydrochloride, a model highly water-soluble drug. Tablets of a hydrophilic matrix composed of dextran derivatives and hypromellose were prepared. The formulations were
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Dextran and Polysaccharides Overview

Dextrans are polysaccharides with molecular weights ≥1,000 Dalton, featuring a linear backbone of α-linked d-glucopyranosyl repeating units.

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