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E0282

MaxGel^™ ECM

Name: MaxGel<SUP>™</SUP> ECM
Brand: SIGMA

mixture, liquid

Synonym(s):

Human Basement Membrane Extract (BME)

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About This Item

UNSPSC Code:

12352207

NACRES:

NA.71

eCl@ss:

32190102

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Quality Level

200

form

liquid

storage temp.

−70°C

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Related Categories

3D Cell Culture Techniques

Cell Culture & Analysis

Hydrogels

Molecular Biology & Functional Genomics

Application

MaxGel^™ ECM is used for the following applications:

Extracellular matrix (ECM) protein binding assays
Cell invasion assay
Cell culture

This product creates a three-dimensional environment that improves cellular proflieration by promoting cell growth and migration, and has been shown to aid the proliferation of many types of cells, including human embryonic stem cells, neural stem cells, neurons, glia, astrocytes, fibroblasts, hepatocytes, and keratinocytes.

Other Notes

MaxGel ECM contains human extracellular matrix components including collagens, laminin, fibronectin, tenascin, elastin and a number of proteoglycans and glycosaminoglycans. This basement membrane extract reproduces the cooperative interactions between epithelia and mesenchyme that occur during the development and organotypic cell culture of skin.

Legal Information

MaxGel is a trademark of Sigma-Aldrich Co. LLC

Disclaimer

MaxGel will remain stable for at least 1 year when stored at -70°C.

Storage Class

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Pyrimido[4,5-d]pyrimidin-4(1H)-one derivatives as selective inhibitors of EGFR threonine790 to methionine790 (T790M) mutants.

Tianfeng Xu et al.

Angewandte Chemie (International ed. in English), 52(32), 8387-8390 (2013-06-28)

MiR-125b attenuates human hepatocellular carcinoma malignancy through targeting SIRT6.

Shi Song et al.

American journal of cancer research, 8(6), 993-1007 (2018-07-24)

Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal cancers. It has been demonstrated that aberrant expression of miRNAs plays an important role in HCC development. Here, we observed decreased miR-125b expression status in tumor samples from HCC

Experimental study of vein subvolution combined with neural stem cells to repair sciatic neurologic defects in rats.

Kang Li et al.

International journal of clinical and experimental pathology, 8(9), 10941-10946 (2015-12-01)

This study aims to explore the effects of vein subvolution combined with neural stem cells on nerve regeneration. Animal model of sciatic nerve defects was established with SD rats. A total of 63 SD rats were divided into control group

Molecular analysis of the Acinetobacter baumannii biofilm-associated protein.

H M Sharon Goh et al.

Applied and environmental microbiology, 79(21), 6535-6543 (2013-08-21)

Acinetobacter baumannii is a multidrug-resistant pathogen associated with hospital outbreaks of infection across the globe, particularly in the intensive care unit. The ability of A. baumannii to survive in the hospital environment for long periods is linked to antibiotic resistance

Overexpression of LASP1 is associated with proliferation, migration and invasion in esophageal squamous cell carcinoma.

Bin He et al.

Oncology reports, 29(3), 1115-1123 (2012-12-21)

LIM and SH3 protein 1 (LASP1) is an actin-binding protein which is overexpressed in many types of cancers and plays important roles in cancer progression. however, the role of LASP1 in esophageal squamous cell carcinoma (ESCC) is still unknown. We sought

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MaxGel™ ECM Hydrogel: An In Vitro Human Cell Derived Basement Membrane Extract for 3D Cell Culture Applications

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Global Trade Item Number

SKU	GTIN
E0282-1ML	04061833601051

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