E0502
Elastin–Congo red
elastase substrate
Synonym(s):
Elastin Congo red
General description
Elastin−Congo red is a substrate-dye conjugate and is used in agar medium to probe elastase activity. The presence of elastase functionality leads to cleavage of the dye from the elastin substrate.
Substrate for the estimation of elastase.
Application
Elastin−Congo red has been used as a substrate for neutrophil elastase, salivary elastase and P. aeruginosa.
Other Notes
Elastin impregnated with Congo red dye.
signalword
Danger
hcodes
Hazard Classifications
Carc. 1B - Repr. 2
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
监管及禁止进口产品
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Quorum sensing (QS) and biofilm inhibition are recognized as the novel drug targets for the broad-spectrum anti-infective strategy to combat the infections caused by drug-resistant bacterial pathogens. Many compounds from medicinal plants have been found to demonstrate anti-infective activity. However
Salivary immunity in elderly individuals presented with Candida-related denture stomatitis
Gasparoto T, et al.
Gerodontology, 29(2), e331-e339 (2012)
Development of an agar diffusion method to measure elastase inhibition activity using Elastin-Congo red
Jung KH and Kim HJ
Journal of microbiology and biotechnology, 16(8), 1320-1324 (2006)
Activation pattern of neutrophils from blood of elderly individuals with Candida-related denture stomatitis
Gasparoto TH, et al.
European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology, 31(6), 1271-1277 (2012)
Articles
Elastase application index for understanding leukocyte elastase, a 29KDa serine endoprotease.
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