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Merck
CN

E1408

14-3-3 Eta histidine-tagged human

recombinant, expressed in E. coli, C-terminal, ≥90% (SDS-PAGE), buffered aqueous glycerol solution

Synonym(s):

14-3-3η, 14-3-3F, 14-3-3e, MGC93547, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide, YWHAH, Ywha1

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About This Item

UNSPSC Code:
12352200
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recombinant

expressed in E. coli

assay

≥90% (SDS-PAGE)

form

buffered aqueous glycerol solution

mol wt

~30 kDa (14-3-3 proteins)

shipped in

dry ice

storage temp.

−20°C

Gene Information

Biochem/physiol Actions

14-3-3 proteins are involved in a multitude of biological processes and play a regulatory role in processes such as apoptotic cell death, mitogenic signal transduction, and cell cycle control. 14-3-3η binds various proteins such as the MTLX-2 transcription factor as well as the DNA binding domain of Miz1 transcription factor. 14-3-3η also binds the glucocorticoid receptor, functioning as a positive regulator in the glucocorticoid signaling pathway. 14-3-3η is expressed and regulated in nerve cells.

Physical form

Supplied as a 0.2 μm filtered solution in 50 mM Tris-HCl, pH 7.6, 1 mM EDTA, 1 mM DTT, and 20% glycerol (w/v).


Storage Class

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable



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