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E1904

Ethyl-3,4-dephostatin

Name: Ethyl-3,4-dephostatin
Brand: SIGMA

>99% (HPLC), solid

Synonym(s):

3,4-Dihydroxy-N-ethyl-N-nitrosoaniline

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₀N₂O₃

CAS Number:

237756-11-5

Molecular Weight:

182.18

NACRES:

NA.77

PubChem Substance ID:

24894445

UNSPSC Code:

12352200

MDL number:

MFCD04040000

Assay:

>99% (HPLC)

Form:

solid

Quality level:

100

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Quality Level

100

assay

>99% (HPLC)

form

solid

color

brown

solubility

DMSO: soluble 22 mg/mL, H₂O: soluble 8 mg/mL

storage temp.

2-8°C

SMILES string

CCN(N=O)c1ccc(O)c(O)c1

InChI

1S/C8H10N2O3/c1-2-10(9-13)6-3-4-7(11)8(12)5-6/h3-5,11-12H,2H2,1H3

InChI key

ZTXUSFPBLYQDDN-UHFFFAOYSA-N

Related Categories

Bioactive Small Molecule Inhibitors

Biochem/physiol Actions

Stable analog of dephostatin. Selective inhibitor of protein tyrosine phosphatase 1B and SHPTP-1. Does not inhibit CD45-associated phosphatases.

Features and Benefits

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

Store under nitrogen

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

042K4609

042K46091

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Reactive oxygen species-responsive miR-210 regulates proliferation and migration of adipose-derived stem cells via PTPN2.

J H Kim et al.

Cell death & disease, 4, e588-e588 (2013-04-13)

Hypoxia enhances the proliferation and migration of adipose-derived stem cells (ASCs) via the generation of reactive oxygen species (ROS). Therefore, this study primarily investigated whether or not ROS generation could regulate microRNA-210 (miR-210) expression, and increase proliferation/migration of ASCs. In

Global Trade Item Number

SKU	GTIN
E1904-1MG	04061826674635

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