Quality Level
Assay
≥95%
solubility
H2O: ≥5 mg/mL, clear
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
SMILES string
Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c4cc(O)c(O)c(O)c4
InChI
1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1
InChI key
WMBWREPUVVBILR-WIYYLYMNSA-N
Gene Information
human ... CYP1A2(1544)
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Related Categories
General description
Application
- as an anti-tumor agent on murine TRAMP metastatic prostate cell line by cell proliferation assay, apoptosis detection and modified Boyden-chamber assay
- induces cell death in acute myeloid leukaemia through death associated protein kinase-2 pathway analyzed through cell viability, cell cycle and apoptosis assay
- as an inhibitor of osteoclast differentiation in murine preosteoclast cell line RAW264.7
- to promote myogenic differentiation
Biochem/physiol Actions
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
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Is (-)-Epigallocatechin gallate (Product No. E4143) sterile and tested for endotoxins?
Product No. E4143 ((-)-Epigallocatechin gallate) is not prepared under sterile conditions and has not been tested for endotoxins.
Is (-)-Epigallocatechin gallate (Product No. E4143) for human use
No. Product No. E4143 ((-)-Epigallocatechin gallate) is for laboratory research use only, not for human use.
What is the solubility of (-)-Epigallocatechin gallate (E4143)?
We have tested the solubility of (-)-Epigallocatechin gallate at 5 mg/mL in water.
What is the solution stability of (-)-Epigallocatechin gallate (E4143)?
A solution of (-)-Epigallocatechin gallate in water at a concentration of 0.3 mg/mL was found to have significantly decreased in purity (from 99.6% to 81.7%) after 2.5 hours at room temperature. A similar solution of (-)-Epigallocatechin gallate in water at a concentration of 0.3 mg/mL was found to have decreased in purity only slightly (from 99.5% to 99.3%) after 2.0 hours at 4°C.
Can (-)-Epigallocatechin gallate be determined in plasma and urine?
The determination of (-)-Epigallocatechin gallate in plasma and urine by HPLC has been reported in Cancer Epidemiol. Biomark. Prev., 4, 393 (1995).
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