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E5008

[D-Ala²]-Leucine enkephalin

Name: [<SC>D</SC>-Ala<SUP>2</SUP>]-Leucine enkephalin
Brand: SIGMA

≥97% (HPLC), suitable for ligand binding assays

Synonym(s):

Tyr-D-Ala-Gly-Phe-Leu

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About This Item

Empirical Formula (Hill Notation):

C₂₉H₃₉N₅O₇

CAS Number:

64963-01-5

Molecular Weight:

569.65

NACRES:

NA.26

PubChem Substance ID:

24894597

UNSPSC Code:

12352209

EC Number:

265-291-0

MDL number:

MFCD00076409

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Properties

Product Name

[D-Ala²]-Leucine enkephalin, ≥97% (HPLC)

Quality Segment

200

assay

≥97% (HPLC)

form

powder

technique(s)

ligand binding assay: suitable

color

white

storage temp.

−20°C

SMILES string

CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)C(C)NC(=O)C(N)Cc2ccc(O)cc2)C(O)=O

InChI

1S/C29H39N5O7/c1-17(2)13-24(29(40)41)34-28(39)23(15-19-7-5-4-6-8-19)33-25(36)16-31-26(37)18(3)32-27(38)22(30)14-20-9-11-21(35)12-10-20/h4-12,17-18,22-24,35H,13-16,30H2,1-3H3,(H,31,37)(H,32,38)(H,33,36)(H,34,39)(H,40,41)

InChI key

ZHUJMSMQIPIPTF-UHFFFAOYSA-N

Description

Biochem/physiol Actions

The Enkephalin amid peptide [D-Ala2]-Leucine enkephalin ((DADLE), a delta opioid agonist, is a degradation resistant long-acting Leu-enkephalin analog used to study the signaling pathway of delta opioid receptors.

Other Notes

Potent, long-acting Leu-enkephalin analog that is resistant to enzymatic degradation

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

0000531334

0000445691

0000339074

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Global Trade Item Number

SKU	GTIN
E5008-5MG	04061832820262