E5641
11,12-Epoxy-(5Z,8Z,14Z)-eicosatrienoic acid
~100 μg/mL in ethanol, ≥95%
Synonym(s):
(±)11,12-EpETrE, 11,12-EET
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About This Item
Empirical Formula (Hill Notation):
C20H32O3
CAS Number:
Molecular Weight:
320.47
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352211
EC Number:
200-578-6
MDL number:
Quality Level
assay
≥95%
concentration
~100 μg/mL in ethanol
lipid type
omega FAs
storage temp.
−20°C
SMILES string
CCCCC\C=C\CC1OC1C\C=C\C\C=C\CCCC(O)=O
InChI
1S/C20H32O3/c1-2-3-4-5-9-12-15-18-19(23-18)16-13-10-7-6-8-11-14-17-20(21)22/h6,8-10,12-13,18-19H,2-5,7,11,14-17H2,1H3,(H,21,22)/b8-6+,12-9+,13-10+
InChI key
DXOYQVHGIODESM-ATELOPIESA-N
Packaging
Packaged under argon
signalword
Danger
hcodes
Hazard Classifications
Eye Irrit. 2 - Flam. Liq. 2
Storage Class
3 - Flammable liquids
wgk
WGK 1
flash_point_f
48.2 °F - closed cup
flash_point_c
9 °C - closed cup
Regulatory Information
危险化学品
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Related Content
Yindi Ding et al.
The Journal of pharmacology and experimental therapeutics, 350(1), 14-21 (2014-04-26)
Cytochrome P450-derived epoxides of arachidonic acid [i.e., the epoxyeicosatrienoic acids (EETs)] are important lipid signaling molecules involved in the regulation of vascular tone and angiogenesis. Because many actions of 11,12-cis-epoxyeicosatrienoic acid (EET) are dependent on the activation of protein kinase
Xiaojing Wang et al.
Scandinavian journal of immunology, 90(3), e12791-e12791 (2019-05-28)
The epoxyeicosatrienoic acids (EETs) are products of cytochrome P450 epoxygenases and have recently been found to have an anti-inflammatory activity. However, the role of EETs in non-alcoholic steatohepatitis has not been fully understood. In this study, we investigated the protective
Andrea E Vasconez et al.
Acta physiologica (Oxford, England), 225(1), e13168-e13168 (2018-08-05)
The histone demethylase Jarid1b limits gene expression by removing the active methyl mark from histone3 lysine4 at gene promoter regions. A vascular function of Jarid1b is unknown, but a vasoprotective function to inflammatory and hypertrophic stimuli, like angiotensin II (AngII)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| E5641-25UG | 04061838070814 |