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E7263

Ethynodiol diacetate

Synonym(s):

(3β, 17α)-19-Norpregn-4-en-20-yne-3,17-diol diacetate, 3β,17β-Diacetoxy-17α-ethynyl-4-estrene, Etynodiol acetate

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About This Item

Empirical Formula (Hill Notation):
C24H32O4
CAS Number:
297-76-7
Molecular Weight:
384.51
NACRES:
NA.77
PubChem Substance ID:
24894643
UNSPSC Code:
41116107
EC Number:
206-044-9
MDL number:
MFCD00083326
Quality level:
200
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Quality Level

200

SMILES string

[H][C@]12CC[C@H](OC(C)=O)C=C1CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@]4(OC(C)=O)C#C

InChI

1S/C24H32O4/c1-5-24(28-16(3)26)13-11-22-21-8-6-17-14-18(27-15(2)25)7-9-19(17)20(21)10-12-23(22,24)4/h1,14,18-22H,6-13H2,2-4H3/t18-,19-,20+,21+,22-,23-,24-/m0/s1

InChI key

ONKUMRGIYFNPJW-KIEAKMPYSA-N

Gene Information

human ... PGR(5241)

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wgk

WGK 3

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000276448
0000276448
040H0345V
040H0345

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David A Grimes et al.
The Cochrane database of systematic reviews, (1)(1), CD007541-CD007541 (2010-01-22)
The introduction of a new progestin-only oral contraceptive in Europe has renewed interest in this class of oral contraceptives. Unlike the more widely used combined oral contraceptives containing an estrogen plus progestin, these pills contain only a progestin (progestogen) and
Shin Yasuda et al.
Journal of biochemistry, 137(3), 401-406 (2005-04-06)
Cytosolic sulfotransferases (SULTs) in mammals are involved in the biotransformation and homeostasis of various endogenous and xenobiotic compounds. The current study aimed to examine the sulfation of contraceptive compounds by various human cytosolic SULTs and to investigate the inhibitory effects
"A randomized clinical trial of cementless femoral stems with and without hydroxyapatite/tricalcium-phosphate coating: an 8- to 12-year follow-up study" by Yoon et al.
Daniel Hernandez-Vaquero et al.
The Journal of arthroplasty, 23(3), 486-487 (2008-03-25)
J M Wheeler et al.
The Journal of reproductive medicine, 36(4 Suppl), 340-344 (1991-04-01)
An open-label, phase IV, multicenter survey of obstetrician-gynecologists was conducted to evaluate the efficacy and safety of a low-dose monophasic oral contraceptive, ethynodiol diacetate, 1 mg, with ethinyl estradiol, 35 micrograms. Surveys from 983 community-based physicians reported on 6,382 women.
Contraceptive failure and the progestogen-only pill.
Louise Melvin
The journal of family planning and reproductive health care, 36(3), 182-182 (2010-07-28)
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Global Trade Item Number

SKUGTIN
E7263-500MG04061833605011

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