Key Documents

View All Documentation

E8031

Esmolol hydrochloride

Name: Esmolol hydrochloride
Brand: SIGMA

≥98% (HPLC), β1 adrenoceptor antagonist , solid

Synonym(s):

4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride hydrochloride

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₁₆H₂₆NClO₄

CAS Number:

81161-17-3

Molecular Weight:

331.83

UNSPSC Code:

12352200

PubChem Substance ID:

329799075

NACRES:

NA.77

MDL number:

MFCD00941432

Assay:

≥98% (HPLC)

Form:

solid

Storage condition:

desiccated

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Esmolol hydrochloride, ≥98% (HPLC), solid

assay

≥98% (HPLC)

form

solid

storage condition

desiccated

mp

89.0-90.6 °C

solubility

H₂O: 12 mg/mL

originator

Baxter

storage temp.

2-8°C

SMILES string

Cl.COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1

InChI

1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H

InChI key

GEKNCWBANDDJJL-UHFFFAOYSA-N

Gene Information

human ... ADRB1(153), ADRB2(154)

Description

Application

Esmolol hydrochloride (ESM) may be used as a standard in spectrophotometric and electrochemical method for the determination of ESM in biological samples and pharmaceutical formulations.

Biochem/physiol Actions

Esmolol hydrochloride (ESM) is a class II antiarrhythmic drug. It is used to decrease the force and rate of heart contractions during surgery. Overdose of ESM can lead to side effects such as bradycardia, cardiac arrest, hypoventilation, mood disorder, and coma.

Esmolol hydrochloride is a ultrashort-acting β₁adrenoceptor antagonist (β₁receptor occupancy = 84.7%).

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Still not finding the right product?

Explore all of our products under Esmolol hydrochloride

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c