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EHU008051

MISSION® esiRNA

targeting human DHCR24

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCCGAGGTGTACGACAAGATCTGCAAGGCCGCCAGGCACTGAGCTGGAGCCCGCCTGGAGAGACAGACACGTGTGAGTGGTCAGGCATCTTCCCTTCACTCAAGCTTGGCTGCTTTCCTAGATCCACACTTTCAAAGAGAAACCCCTCCAGAACTCCCACCCTGACAGCCCAACACCACCTTCCTCCTGGCTTCCAGGGGGCAGCCCAGTGGAATGGAAAGAATGTGGGATTTGGAGTCAGACAAGCCTGAGTCCAGTTCCCCGTTTAGAACTCATTAGCTGTGTGACTCTGGGTGAGTCCCTTAACCCCTCTGAGCCCGGGTCTCTTCATTAGTTGAAAGGGATAGTAATACCTACTTGCAGGTTGTTGTCATCTGAGTTGAGCACTGGTCACATTGAAGGTGCTGGGTAAGTGGTAGCTCTTGTTGCTTCCCG

Ensembl | human accession no.

ENSG00000116133

NCBI accession no.

NM_014762

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... DHCR24(1718)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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MISSION esiRNA

Instructions

Jie Wu et al.
British journal of cancer, 123(11), 1673-1685 (2020-09-23)
The liver is the central organ for cholesterol homoeostasis, and its dysfunction might cause liver pathological alterations including hepatocellular carcinomas (HCCs). 3β-hydroxysteroid-Δ24 reductase (DHCR24), a crucial enzyme of cholesterol biosynthetic pathway, is involved in lipid rafts formation. Genkwadaphnin (GD) is

Global Trade Item Number

SKUGTIN
EHU008051-20UG04061831360929
EHU008051-50UG04061828454716