产品名称
MISSION® esiRNA, targeting human DHCR24
description
Powered by Eupheria Biotech
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CCCGAGGTGTACGACAAGATCTGCAAGGCCGCCAGGCACTGAGCTGGAGCCCGCCTGGAGAGACAGACACGTGTGAGTGGTCAGGCATCTTCCCTTCACTCAAGCTTGGCTGCTTTCCTAGATCCACACTTTCAAAGAGAAACCCCTCCAGAACTCCCACCCTGACAGCCCAACACCACCTTCCTCCTGGCTTCCAGGGGGCAGCCCAGTGGAATGGAAAGAATGTGGGATTTGGAGTCAGACAAGCCTGAGTCCAGTTCCCCGTTTAGAACTCATTAGCTGTGTGACTCTGGGTGAGTCCCTTAACCCCTCTGAGCCCGGGTCTCTTCATTAGTTGAAAGGGATAGTAATACCTACTTGCAGGTTGTTGTCATCTGAGTTGAGCACTGGTCACATTGAAGGTGCTGGGTAAGTGGTAGCTCTTGTTGCTTCCCG
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
Gene Information
human ... DHCR24(1718), DHCR24(1718)
General description
MISSION® shRNA是核糖核酸内切酶制备的siRNA。它们是靶向相同mRNA序列的siRNA异质混合物。这些多重沉默触发（multiple silencing trigger）导致高度特异性的、有效的基因沉默。
如需其他详细信息并查看所有可用的esiRNA选项，请访问SigmaAldrich.com/esiRNA。
如需其他详细信息并查看所有可用的esiRNA选项，请访问SigmaAldrich.com/esiRNA。
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Jie Wu et al.
British journal of cancer, 123(11), 1673-1685 (2020-09-23)
The liver is the central organ for cholesterol homoeostasis, and its dysfunction might cause liver pathological alterations including hepatocellular carcinomas (HCCs). 3β-hydroxysteroid-Δ24 reductase (DHCR24), a crucial enzyme of cholesterol biosynthetic pathway, is involved in lipid rafts formation. Genkwadaphnin (GD) is
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