EHU011891
MISSION® esiRNA
targeting human RNF168
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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
TATCTCGGCTTCTCCCTTGAATTCCAGAAAATCTGATCCAGTTACACCCAAGTCTGAAAAGAAAAGTAAGAACAAACAAAGAAACACTGGAGATATTCAGAAGTATTTGACACCGAAATCTCAGTTTGGGTCAGCCTCACACTCTGAAGCTGTACAAGAAGTCAGGAAAGACTCCGTATCTAAGGACATTGACAGTAGTGATAGGAAAAGCCCAACAGGGCAAGACACAGAAATAGAAGATATGCCGACACTTTCTCCACAGATATCCCTTGGAGTTGGAGAACAAGGTGCAGATTCTTCAATAGAGTCCCCTATGCCATGGTTATGTGCCTGTGGTGCCGAATGGTACCATGAAGGAAACGTCAAAACAAGACCAAGCAATCATGGGAAAGAGTTATGTGTCTTAAGTCACGAGCGACCTAAAACCAGA
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... RNF168(165918)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Related Content
Instructions
Stanimir Dulev et al.
Cell cycle (Georgetown, Tex.), 19(1), 15-23 (2019-11-26)
The DNA damage response (DDR) associated post-translational modifications recruit chromatin remodelers, signaling proteins such as 53BP1 and repair factors to chromatin flanking DNA double strand breaks (DSBs) to promote its repair. Although localization of both RNF168 ubiquitin ligase and SET8
Parasvi S Patel et al.
The Journal of clinical investigation, 131(3) (2021-02-03)
Germline mutations in BRCA1 and BRCA2 (BRCA1/2) genes considerably increase breast and ovarian cancer risk. Given that tumors with these mutations have elevated genomic instability, they exhibit relative vulnerability to certain chemotherapies and targeted treatments based on poly (ADP-ribose) polymerase
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EHU011891-20UG | 04061831361506 |
| EHU011891-50UG | 04061831370690 |