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Merck
CN

EHU033171

Sigma-Aldrich

MISSION® esiRNA

targeting human BLMH

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

Key Documents

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description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AACAGAGGCAACCAGAAGGATGAATGATATTCTGAATCACAAGATGAGAGAATTCTGTATACGACTGCGGAACCTGGTACACAGTGGAGCAACCAAAGGAGAAATCTCGGCCACACAGGACGTCATGATGGAGGAGATATTCCGAGTGGTGTGCATCTGTTTGGGTAATCCACCAGAGACATTCACCTGGGAATATCGAGACAAAGATAAAAATTATCAGAAAATTGGCCCCATAACACCCTTGGAGTTTTACAGGGAACATGTCAAGCCACTCTTCAATATGGAAGATAAGATTTGTTTAGTGAATGACCCTAGGCCCCAGCACAAGTACAACAAACTTTACACAGTGGAATACTTAAGCAATATGGTTGGAGGGAGAAAAACTCTATACAACAACCAGCCCATTGACTTCCTGAAAAAGATGGTTGCTGCCTCCATCAAAGATGGAGAGGCTGTGTGGTTTGGCTGTGATGTT

Ensembl | human accession no.

ENSG00000108578

NCBI accession no.

NM_000386

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... BLMH(642), BLMH(642)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Rebecca Riise et al.
Scientific reports, 9(1), 20407-20407 (2020-01-02)
Bleomycin hydrolase (BLMH) is a well-conserved cysteine protease widely expressed in several mammalian tissues. In skin, which contains high levels of BLMH, this protease is involved in the degradation of citrullinated filaggrin monomers into free amino acids important for skin

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