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EHU049221

MISSION® esiRNA

targeting human CDCP1

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CCCAACAATGGGGATGTAAGCAGCAAGGACACAGACATTCCCTTACTGAACACTCAGGAGCCCATGGAGCCAGCAGAATAACTTGATCCATTCCAGACGCTTTGCTGAGTTTCATAAAGCAGGGCACTGAGACACCCGTCCGTGTTCCTAACCAGAAATCCTAAAGAAGAGGAATTATACAGAAGGAACAGCAGGAGGTTTTCCTGGACACCGCCAACTTCACATTGCTCAGTGGACTCATTCTAAGGGCAAGACATTGAAAATGATGAATTCCAATCTGGATACAGTCATGACAGCTCATGTGCTCCTCAACTTAGGCTGTGCGGTTAGCCAGCCTGTAATGAGAGGAGAGAGGCCTGAGTCACCTAGCATAGGGTTGCAGCAAGCCCTGGATTCAGAGTG

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... CDCP1(64866)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Lijun Huang et al.
Cancer management and research, 12, 3759-3769 (2020-06-18)
Emerging evidence have revealed significant contributions of CUB domain-containing protein-1 (CDCP1) in tumorigenesis, including colon, renal, ovarian, pancreatic, prostate and breast cancers. However, the roles of CDCP1 in cervical cancer (CC) still remain elusive. Quantitative reverse transcription polymerase chain reaction
Nina Noskovičová et al.
American journal of physiology. Lung cellular and molecular physiology, 314(5), L695-L707 (2018-01-20)
Fibroblasts are thought to be the prime cell type for producing and secreting extracellular matrix (ECM) proteins in the connective tissue. The profibrotic cytokine transforming growth factor-β1 (TGF-β1) activates and transdifferentiates fibroblasts into α-smooth muscle actin (α-SMA)-expressing myofibroblasts, which exhibit



Global Trade Item Number

SKUGTIN
EHU049221-20UG04061828570621
EHU049221-50UG04061828335299