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EHU071161

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting human TPCN2

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NACRES:

NA.51

UNSPSC Code:

41105324

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Properties

description

Quality Level

100

product line

MISSION^®

form

lyophilized powder

esiRNA cDNA target sequence

TCTCTCCAGACCTCGCTGTTTCGGAGGCGGCTGGGAACCCGGGCTGCCTTTGAAGTCCTATCCTCCATGGTGGGGGAGGGAGGAGCCTTCCCTCAGGCAGTTGGGGTGAAGCCCCAGAACTTGCTGCAGGTGCTTCAGAAGGTCCAGCTGGACAGCTCCCACAAACAGGCCATGATGGAGAAGGTGCGTTCCTATGGCAGTGTTCTGCTCTCAGCTGAGGAGTTTCAGAAGCTCTTCAACGAGCTTGACAGAAGTGTGGTTAAAGAGCACCCGCCGAGGCCCGAGTACCAGTCTCCGTTTCTGCAGAGCGCCCAGTTCCTCTTCGGCCACTACTACTTTGACTACCTGGGGAACCTCATCGCCCTGGCAAACCTGGTGTCCATTTGCGTGTTCCTGGTGCTGGATGCAGATGTGCTGCCTGCTGAGCGTGATGACTTCATCCTGGGGATTCTCA

Ensembl | human accession no.

ENSG00000162341

NCBI accession no.

NM_139075

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... TPCN2(219931)

Description

General description

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

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Not applicable

flash_point_c

Not applicable

Regulatory Information

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Loss of Two-Pore Channel 2 (TPC2) Expression Increases the Metastatic Traits of Melanoma Cells by a Mechanism Involving the Hippo Signalling Pathway and Store-Operated Calcium Entry.

Antonella D'Amore et al.

Cancers, 12(9) (2020-08-28)

Melanoma is one of the most aggressive and treatment-resistant human cancers. The two-pore channel 2 (TPC2) is located on late endosomes, lysosomes and melanosomes. Here, we characterized how TPC2 knockout (KO) affected human melanoma cells derived from a metastatic site.

Global Trade Item Number

SKU	GTIN
EHU071161-20UG	04061828610754
EHU071161-50UG	04061828371136

Key Documents

MISSION^® esiRNA

targeting human TPCN2

Select a Size

About This Item

description

Quality Level

product line

form

esiRNA cDNA target sequence

Ensembl | human accession no.

NCBI accession no.

shipped in

storage temp.

Gene Information

General description

Legal Information

Safety Information

Storage Class

flash_point_f

flash_point_c

Regulatory Information

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Peer Reviewed Papers

Global Trade Item Number

Key Documents

MISSION® esiRNA

targeting human TPCN2

Select a Size

About This Item

description

Quality Level

product line

form

esiRNA cDNA target sequence

Ensembl | human accession no.

NCBI accession no.

shipped in

storage temp.

Gene Information

General description

Legal Information

Safety Information

Storage Class

flash_point_f

flash_point_c

Regulatory Information

Documentation

Certificates of Analysis (COA)

Already Own This Product?

Peer Reviewed Papers

Global Trade Item Number

MISSION^® esiRNA