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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CTGCAAGGTGGACAAACAGAACCGTGCTGGCTACAGCCCTATTATGCTCACCGCCCTGGCCACCCTGAAGACCCAGGACGACATCGAGACTGTCCTTCAGCTCTTCCGGCTTGGCAACATCAATGCCAAAGCCAGCCAGGCAGGACAGACGGCCCTGATGCTGGCCGTCAGCCACGGGCGGGTGGACGTTGTCAAAGCCCTGCTGGCCTGTGAGGCAGATGTCAACGTGCAAGATGATGACGGCTCCACGGCCCTCATGTGCGCCTGTGAGCACGGCCACAAGGAGATCGCGGGGCTGCTGCTGGCCGTGCCCAGCTGTGACATCTCACTCACAGATCGCGATGGGAGCACAGCTCTGATGGTGGCCTTGGACGCAGGGCAGAGTGAGATTGCGTCCATGCTGTA
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... KANK2(25959)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Mladen Paradžik et al.
Frontiers in cell and developmental biology, 8, 125-125 (2020-03-21)
Integrins are heterodimeric glycoproteins that bind cells to extracellular matrix. Upon integrin clustering, multimolecular integrin adhesion complexes (IACs) are formed, creating links to the cell cytoskeleton. We have previously observed decreased cell migration and increased sensitivity to microtubule (MT) poisons
Nisha Bte Mohd Rafiq et al.
Nature materials, 18(6), 638-649 (2019-05-23)
The interrelationship between microtubules and the actin cytoskeleton in mechanoregulation of integrin-mediated adhesions is poorly understood. Here, we show that the effects of microtubules on two major types of cell-matrix adhesion, focal adhesions and podosomes, are mediated by KANK family
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EHU079121-50UG | 04061828402557 |
| EHU079121-20UG | 04061828630042 |