EHU083491
MISSION® esiRNA
targeting human LRSAM1
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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
AACGCCTGGAGTACCAGATGTGTTTGGCAAAAGAAGCTGGGGCAGATGACATTCTCGACATCTCTAAATGTGAGCTCTCAGAGATTCCATTTGGAGCTTTTGCAACATGCAAAGTTCTGCAGAAGAAGGTGCTGATCGTCCACACGAATCACCTCACTTCCCTGCTTCCCAAATCCTGCAGCCTCCTGAGTCTGGCAACCATCAAGGTTCTAGATCTCCACGATAATCAGCTGACAGCCCTTCCTGACGATCTGGGGCAGCTGACTGCCCTCCAGGTCTTAAACGTGGAAAGGAATCAACTGATGCAGCTCCCACGTTCCATTGGGAACCTGACCCAGCTCCAGACTCTCAATGTTAAAGACAACAAGCTGAAGGAGCTTCCAGACACCGTGGGGGAGCTTCGAAGCCTGCGTACCCTCAACATCAGTGGAAACG
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... LRSAM1(90678)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Ribhav Mishra et al.
The international journal of biochemistry & cell biology, 120, 105697-105697 (2020-01-27)
Accumulation of aberrant misfolded proteins is a major hallmark of several neurodegenerative diseases. Intracellular accumulations of such abnormal proteins are selectively cleared by the ubiquitin-proteasome system (UPS). But how the failure of misfolded protein degradation cause proteinopathies is still an
Anna Minaidou et al.
Cell journal, 20(3), 340-347 (2018-05-31)
Deleterious variants in LRSAM1, a RING finger ubiquitin ligase which is also known as TSG101-associated ligase (TAL), have recently been associated with Charcot-Marie-Tooth disease type 2P (CMT2P). The mechanism by which mutant LRSAM1 contributes to the development of neuropathy is
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EHU083491-50UG | 04061828395255 |
| EHU083491-20UG | 04061831354362 |