EHU086361
MISSION® esiRNA
targeting human SLFN11
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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
CTGCAGAAGCATGGTCTGTTAGGAGCTTACTGGCCGTAGCAGAAGCAATTGTTTCCTGAATTCTTGACATTTATCTTTGCTGTATTCATTTAGGGCTTGGGAGAGTCCGAAGATAATTCAGTCACTGTCAGATTAATAATTTTGTCAGGACAAAGAATACCGTTATGATTATTTAATCCTTTAAAATTGTGGTCTCCAGAGCTTGTTCTCAGAATGGCCCAGACCAAGCCTTAATTGTGATAGTGAATATTAATGGTCACTTTAAGGAGAAATTATAGGCCAAGATGAAATGAACATAAACCTGTTTGCCCTGGCTTTCAGTGGAAGATGATATTAGAGACCAAAATCTGGTTCTGAAGGTGTGTATCAGCCCTAAGGTGAACCAGACTTGGGAAAGATTG
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... SLFN11(91607)
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Shenlan Mao et al.
Molecular cancer therapeutics, 20(3), 541-552 (2021-03-04)
Resistance to antibody-drug conjugates (ADCs) has been observed in both preclinical models and clinical studies. However, mechanisms of resistance to pyrrolobenzodiazepine (PBD)-conjugated ADCs have not been well characterized and thus, this study was designed to investigate development of resistance to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EHU086361-20UG | 04061828621811 |
| EHU086361-50UG | 04061828388448 |