EHU093681
MISSION® esiRNA
targeting human BLOC1S5
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About This Item
NACRES:
NA.51
UNSPSC Code:
41105324
description
Powered by Eupheria Biotech
Quality Level
product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
ACCGTTTAGCCTCTGCTTCAAGCTTAGCAATATATTCAGTGGCACTCTTATATCAGAAGAAAGAAGTTTCTACTGGCATTCTGATTGGATATTTAAAGAAGGGTGCCACATTTTTCCAGCTTTAAGTGCCTATATATGATTATTTGAATGAAGAGGAGTAGGAAGGAAAATGGAATCAATATACTCTTTGTTAGTCAGAATTGATCATCTTTTCCATTGATTAGCTCAGAGAACTGTAGGTATAGACTTCTTAGAAAGATAATTTCATTCATTTCTATACAGGGTTAACAATAGTTTATTATTGTGGCTTAATGGGAAGGTATAGAAGCTACCTGTCATAGCCTCCTTGGCTGTTGGAAGGATGT
Ensembl | human accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Gene Information
human ... BLOC1S5(63915), TXNDC5(63915)
General description
MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Wilhelmina C M Duivenvoorden et al.
Oncology letters, 13(5), 3624-3630 (2017-05-20)
Endoplasmic reticulum (ER) protein ERp46 is a member of the protein disulfide isomerase family of oxidoreductases, which facilitates the reduction of disulfides in proteins and their folding. Accumulation of misfolded proteins has been implicated in cancer. The objectives of the
L Wang et al.
Oncogene, 34(36), 4735-4745 (2014-12-17)
Castration-resistant prostate cancer (CRPC) continues to be a major clinical problem and the mechanisms behind it remain unclear. Thioredoxin domain-containing protein 5 (TXNDC5) is involved in protein folding and chaperone activity, and its overexpression has been reported in multiple malignancies.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| EHU093681-50UG | 04061828363292 |
| EHU093681-20UG | 04061828598014 |