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Merck
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EHU094471

MISSION® esiRNA

targeting human KAT8

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CGCTGACCAAGACAGTGAAGGATGCTGTACAGAAGAACTCAGAGAAGTACCTGAGCGAGCTCGCAGAGCAGCCTGAGCGCAAGATCACTCGCAACCAAAAGCGCAAGCATGATGAGATCAACCATGTGCAGAAGACTTATGCAGAGATGGACCCCACCACAGCAGCCTTGGAGAAGGAGCATGAGGCGATCACCAAGGTGAAGTATGTGGACAAGATCCACATCGGGAACTACGAAATTGATGCCTGGTATTTCTCACCATTCCCCGAAGACTATGGGAAACAGCCCAAGCTCTGGCTCTGCGAGTACTGCCTCAAGTACATGAAATATGAGAAGAGCTACCGCTTCCACTTGGGTCAGTGCCAGTGGCGGCAGCCCCCCGGGAAAGAGATCTACCGCAAGAGCAACATCTCCGTGTACGAA

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany


Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Jin Zhang et al.
Biochemical and biophysical research communications, 452(3), 575-580 (2014-09-03)
Males absent on the first (MOF) is a histone acetyltransferase belongs to the MYST (MOZ, Ybf2/Sas3, Sas2 and TIP60) family. In mammals, MOF plays critical roles in transcription activation by acetylating histone H4K16, a prevalent mark associated with chromatin decondensation.
Zhiwei Chen et al.
British journal of pharmacology, 171(13), 3196-3211 (2014-02-28)
The histone acetyltransferase MOF is a member of the MYST family. In mammals, MOF plays critical roles by acetylating histone H4 at K16 and non-histone substrates such as p53. Here we have investigated the role of MOF in human lung



Global Trade Item Number

SKUGTIN
EHU094471-20UG04061828598687
EHU094471-50UG04061831374155