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Merck
CN

EHU098401

Sigma-Aldrich

MISSION® esiRNA

targeting human VPS50

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGGCCTTCTTGCAAATCAAAGGAAACGTCAGTTGCTGATTGGACTTCTGAAATCTCTGAGAACTATAAAAACATTGCAAAGAACAGATGTACGGTTAAGTGAAATGCTGGAGGAGGAAGATTATCCAGGAGCTATTCAGTTGTGCCTTGAATGTCAAAAAGCTGCCAGCACTTTTAAACATTACAGTTGTATAAGTGAACTGAATTCAAAGCTGCAAGATACTTTGGAACAGATTGAGGAACAGCTGGACGTAGCTC

Ensembl | human accession no.

ENSG00000004766

NCBI accession no.

NM_017667

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... VPS50(55610), CCDC132(55610)

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Simon Gemble et al.
PLoS genetics, 11(7), e1005384-e1005384 (2015-07-17)
Genome stability is jeopardized by imbalances of the dNTP pool; such imbalances affect the rate of fork progression. For example, cytidine deaminase (CDA) deficiency leads to an excess of dCTP, slowing the replication fork. We describe here a novel mechanism

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