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Merck
CN

EHU111741

Sigma-Aldrich

MISSION® esiRNA

targeting human SPECC1L, SPECC1L-ADORA2A

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
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description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GATCTGGCTCATACCCGAAATGATGCCAATCGATTACAGGATGCCATTGCTAAGGTAGAGGATGAATACCGAGCCTTCCAAGAAGAAGCTAAGAAACAAATTGAAGATTTGAATATGACGTTAGAAAAATTAAGATCAGACCTGGATGAAAAAGAAACAGAAAGGAGTGACATGAAAGAAACCATCTTTGAACTTGAAGATGAAGTAGAACAACATCGTGCTGTGAAACTTCATGACAACCTCATTATTTCTGATCTAGAGAATACAGTTAAAAAACTCCAGGACCAAAAGCACGACATGGAAAGAGAAATAAAGACACTCCACAGAAGACTTCGGGAAGAATCTGCGGAATGGCGGCAGTTTCAGGCTGATCTCCAGACTGCAGTAGTCATTGCAAATGACATTAAATCTGAAGCCCAAGAGGAGATTGGTGATCTAAAGCGCCGGTTA

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

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Qingle Liang et al.
Nature biomedical engineering, 3(9), 729-740 (2019-05-22)
Extracellular microparticles (MPs) can function as drug-delivery vehicles for anticancer drugs. Here, we show that the softness of MPs derived from tumour-repopulating cells (TRCs) isolated from three-dimensional fibrin gels enhances the MPs' drug-delivery efficiency. We found that, compared with MPs

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