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Merck
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EHU138941

MISSION® esiRNA

targeting human TBX2

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

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description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGGACCAGTTCCACAAGCTAGGCACGGAGATGGTCATCACCAAGTCCGGGAGGCGGATGTTCCCCCCCTTCAAGGTGCGAGTCAGCGGCCTGGACAAGAAGGCCAAGTATATCCTGCTGATGGACATTGTAGCCGCTGACGATTGCCGCTATAAGTTCCACAACTCGCGCTGGATGGTGGCGGGCAAGGCCGACCCTGAGATGCCCAAACGCATGTACATCCACCCAGACAGCCCAGCCACGGGGGAGCAGTGGATGGCTAAGCCTGTGGCCTTCCACAAGCTGAAGCTGACCAACAACATCTCTGACAAGCACGGCTTCACCATCCTAAACTCCATGCACAAGTACCAGCCGCGCTTCCACATAGTGCGAGCCAACGACATCCTGAAGCTGCCTTACAGCACCTTCCGCACCTACGTGTTCCCGGAGACCGACTTCATCGCCGTCACTGCCTACCAGAATGACAAGATCACACAGCTGAAGATCGACAACAACCCGT

Ensembl | human accession no.

ENSG00000121068

NCBI accession no.

NM_005994

shipped in

ambient

storage temp.

−20°C

Quality Level

100

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Jerome Perrard et al.
Oncology letters, 19(1), 1074-1081 (2020-01-04)
HPV16 is the most carcinogenic human papillomavirus and causes >50% of cervical cancers, the majority of anal cancers and 30% of oropharyngeal squamous cell carcinomas. HPV carcinogenesis relies on the continuous expression of the two main viral oncoproteins E6 and
Wen-Liang Du et al.
Molecular medicine reports, 16(5), 6050-6058 (2017-08-30)
T‑Box (TBX)‑2 is a member of the T‑box gene family, which is aberrantly expressed in numerous types of malignant tumors, and has previously been demonstrated to be conducive to tumor progression by acting as a transcription factor. However, specific information

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