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Merck
CN

EMU004141

MISSION® esiRNA

targeting mouse Plxna4

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

Key Documents

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description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CATCAAGCAGCAGATGGAGAAGGGCCCCATTGATGCCATCACCGGAGAGGCCCGCTACTCGCTAAGTGAGGACAAACTCATCCGACAGCAGATTGAATATAAAACCTTGGTCCTGAGCTGTGTCAGTCCAGATAATGTTAACAGCCCAGAGGTCCCAGTGAAGATCCTCAACTGTGACACCATCACTCAGGTCAAAGAGAAGATCCTAGATGCCATCTTCAAGAATGTCCCGTGCTCCCATAGGCCCAAAGCTGCAGACATGGATCTAGAGTGGCGACAAGGAAGTGGGGCGAGGATGATCCTGCAGGACGAAGATATCACCACCAAGATCGAGAATGATTGGAAGAGACTCAACACAGTAGCCCACTACCAGGTACCAGATGGTTCTGTGGTGGCTTTAGTGTCCA

Ensembl | mouse accession no.

ENSMUSG00000029765

NCBI accession no.

NM_175750

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... PLXNA4(243743), Plxna4(243743)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Sujin Kang et al.
Nature immunology, 19(6), 561-570 (2018-05-20)
Polarization of macrophages into pro-inflammatory or anti-inflammatory states has distinct metabolic requirements, with mechanistic target of rapamycin (mTOR) kinase signaling playing a critical role. However, it remains unclear how mTOR regulates metabolic status to promote polarization of these cells. Here

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