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Merck
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EMU019891

MISSION® esiRNA

targeting mouse Rnf5

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

Key Documents

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Product Name

MISSION® esiRNA, targeting mouse Rnf5

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AATGCCCATGAACCTTTCAGAAGAGGCGCAGGTGTGGATCTGGGACAGGGTCACCCAGCCTCCAGCTGGCAAGATTCCCTATTCCTGTTCCTCGCCATCTTTTTCTTTTTCTGGCTGCTCAGTATTTGAGCTCTGTCTCCTCCCTGCCCACCTCCAGCTAGAGGAGAATCAGTATTGGGAGTCCTGTGCTGGCCTTTCCTTGCTTTTGGACCACCCCCTTACTTCCATGACCCATCTCTGTCTGCTGAGGCCTCTCTCTTGGGAGGGCATGGCGAGGAGTGACCAGTCTGCTTAAGATGGGAGTGCCTGCTGCTGTGTACTGCTGGCCCAGTAGCACAGACACTGTCAGCCTGGAGGACGGACAGACAGACAGGTGTCCAGTTCTCCCAATCCTTTGCTTTCCCCCAGATTTCTTGATTTGGTGTTTAAAGGTGGGCTC

Ensembl | mouse accession no.

ENSMUSG00000015478

NCBI accession no.

NM_019403

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... RNF5(54197), Rnf5(54197)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Sridevi Yadavilli et al.
Oncotarget, 6(14), 12141-12155 (2015-05-20)
Diffuse intrinsic pontine gliomas (DIPGs) have a dismal prognosis and are poorly understood brain cancers. Receptor tyrosine kinases stabilized by neuron-glial antigen 2 (NG2) protein are known to induce gliomagenesis. Here, we investigated NG2 expression in a cohort of DIPG
Frank Maus et al.
PloS one, 10(9), e0137311-e0137311 (2015-09-05)
The NG2 proteoglycan is characteristically expressed by oligodendrocyte progenitor cells (OPC) and also by aggressive brain tumours highly resistant to chemo- and radiation therapy. Oligodendrocyte-lineage cells are particularly sensitive to stress resulting in cell death in white matter after hypoxic

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