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EMU036141

MISSION® esiRNA

targeting mouse Ruvbl2

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AAGGTGGCTGAGTGGAGAGAGGAGGGCAAGGCAGAGATCATTCCTGGGGTGCTGTTCATCGACGAGGTCCACATGCTGGACATTGAGAGTTTCTCTTTCCTCAACCGGGCCCTGGAGAGCGACATGGCGCCTGTCCTCATCATGGCCACCAACCGAGGGATCACCCGGATCCGAGGCACCAGCTACCAGAGTCCCCACGGCATCCCCATCGACCTGCTGGACCGCTTGCTCATTGTATCAACGTCACCCTACAGTGAGAAGGATACCAAGCAGATTCTGCGCATCCGCTGTGAGGAGGAAGATGTGGAGATGAGTGAGGACGCCTACACAGTGCTGACCCGCATTGGGCTCGAGACCTCCCTGCGCTATGCCATCCAGCTCATCACAGCGGCCAGCCTGGTGTGCCGGAAACGAAAGGGCACCGAGGTGCAGGTCGATGACATTAAGCGTGTATACTCCCTCTTCCTGGATGAATCCCGCTCCACACAGTAC

Ensembl | mouse accession no.

ENSMUSG00000003868

NCBI accession no.

NP_035434

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... RUVBL2(20174), Ruvbl2(20174)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Wenjuan Li et al.
Molecular cancer, 9, 132-132 (2010-06-01)
Telomerase is activated in oncogenesis, which confers an immortal phenotype to cancer cells. The AAA + ATPase Reptin is required for telomerase biogenesis by maintaining telomerase RNA (hTER) stability and is aberrantly expressed in certain cancers. Given its role in
Mathieu Dalvai et al.
PLoS genetics, 9(4), e1003387-e1003387 (2013-05-03)
Histone variants, including histone H2A.Z, are incorporated into specific genomic sites and participate in transcription regulation. The role of H2A.Z at these sites remains poorly characterized. Our study investigates changes in the chromatin environment at the Cyclin D1 gene (CCND1)

Global Trade Item Number

SKUGTIN
EMU036141-20UG04061828496303
EMU036141-50UG04061828271047