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EMU043481

MISSION® esiRNA

targeting mouse Serpinh1

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTGCGAACACTCCAAGATCAACTTCCGAGACAAGCGCAGCGCCCTGCAGTCCATCAACGAGTGGGCCTCGCAGACCACGGACGGCAAGCTGCCTGAGGTCACCAAGGATGTGGAGCGCACGGATGGGGCACTGCTTGTGAACGCCATGTTCTTTAAGCCACACTGGGATGAGAGGTTTCACCACAGGATGGTGGACAACCGTGGCTTCATGGTGACCCGCTCCTATACTGTGGGTGTTACGATGATGCACCGGACAGGCCTGTACAACTACTATGACGACGAGAAGGAGAAGCTGCAGATGGTGGAGATGCCCCTGGCTCACAAGCTCTCCAGCCTCATCATCCTCATGCCCCACCATGTGGAGCCGCTCGAGCGCTTGGAGAAGCTGCTGACCAAGGAGCAGCTGAAGGCCTGGATGGGAAAGATGCAGAAGAAGGCTGTCGCCATCTCCCTGCCCAAGGGCGTGGTGGAGGTGACCCATGACCTGCAGAAACATCTGGCAGGACTGGGCCTGACCGAAGCCATCGACAAGAACAAGGCAGACCTATCGC

Ensembl | mouse accession no.

ENSMUSG00000070436

NCBI accession no.

NM_009825

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... SERPINH1(12406), Serpinh1(12406)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Jingga Morry et al.
Biomaterials, 66, 41-52 (2015-07-22)
Fibrotic diseases such as scleroderma have been linked to increased oxidative stress and upregulation of pro-fibrotic genes. Recent work suggests a role of NADPH oxidase 4 (NOX4) and heat shock protein 47 (HSP47) in inducing excessive collagen synthesis, leading to
Haiyan Chu et al.
Protein & cell, 6(8), 589-598 (2015-06-21)
Uncontrolled fibrosis of skin and internal organs is the main characteristic of scleroderma, and collagen is a major extracellular matrix protein that deposits in the fibrotic organs. As the chaperone of collagen, heat shock protein 47 (HSP47) is closely related

Global Trade Item Number

SKUGTIN
EMU043481-20UG04061828500512
EMU043481-50UG04061828274970