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EMU045261

MISSION® esiRNA

targeting mouse Mapre2

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CAAGCAAAGTTGGAGCATGAGTATATTCACAACTTTAAACTTCTGCAAGCATCCTTTAAACGGATGAATGTTGATAAGGTAATCCCAGTGGAGAAGCTGGTGAAAGGGCGTTTCCAAGACAACCTGGATTTTATTCAGTGGTTTAAGAAGTTCTACGATGCTAACTATGACGGGAAGGAGTACGATCCTGTTGAGGCCCGACAAGGGCAAGATGCAATTCCTCCCCCTGACCCTGGTGAACAGATCTTCAACCTGCCCAAGAAGTCGCACCATGCAAACTCCCCCACAGCAGGCGCGGCTAAGTCAAGTCCTGCATCTAAGCCAGGATCCACACCTTCTCGCCCCTCGTCTGCCAAAAGGGCTTCATCCAGTGGCTCTGCATCCAGATCTGACAAAGATTTAGAAACGCAGGTCATACAGCTCAACGAGCAGGTACATTCATTGAAACTCGCCCTAGAAGGTGTGGAGAAGGAGAGGGATTTCTACTTCGGGAAGTTGAGAGAGATTGAGCTGCTGTGCCAAGAACATGGGCAGGAGAACGATGACCTCGTGCAGCGACTAATGGAAGTGCTCTACGCTTCCGATGAAC

Ensembl | mouse accession no.

ENSMUSG00000024277

NCBI accession no.

NM_153058

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... MAPRE2(212307), Mapre2(212307)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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S-C Tien et al.
Oncogene, 33(22), 2938-2946 (2013-06-19)
Deregulation of Shp2, a non-receptor tyrosine phosphatase, causes hyperactivation of extracellular signal-regulated kinase (ERK), leading to growth abnormality. Here, we show that inhibition of RhoA-Dia is sufficient to upregulate ERK activation in epithelial cells. Oncogenic Shp2 expression attenuates RhoA-Dia signaling

Global Trade Item Number

SKUGTIN
EMU045261-50UG04061828276714
EMU045261-20UG04061828488575

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