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EMU050341

MISSION® esiRNA

targeting mouse Sesn2

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TAGCCTGCAGCCTCACCTATAACACCATCGCCATGCACAGTGGCGTGGACACCTCCATGCTCCGCAGGGCCATCTGGAACTACATCCACTGCGTCTTTGGCATCAGATACGATGACTATGATTACGGCGAGGTAAACCAGCTCCTGGAACGGAACCTCAAAATCTATATCAAGACGGTGGCCTGCTACCCTGAGAAGACGACCCGTAGGATGTACAACCTCTTTTGGAGGCACTTCCGCCACTCAGAGAAGGTTCATGTGAACTTGCTGCTCCTTGAAGCCCGCATGCAAGCGGCCCTGCTCTATGCCCTGCGCGCCATCACCCGCTACATGACCTGACTACCCCGTACGCAGGACCAGCACCAGGAGCAGCTGACCCTGGTCCACCGTCCTCTGTGCAAGGACTTCTGTGTCTGGAGACAGATCTGGGAAGG

Ensembl | mouse accession no.

ENSMUSG00000028893

NCBI accession no.

NM_144907

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... SESN2(230784), Sesn2(230784)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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MWT

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Hiroko Hamatani et al.
American journal of physiology. Renal physiology, 307(6), F708-F717 (2014-07-25)
Sestrin 2, initially identified as a p53 target protein, accumulates in cells exposed to stress and inhibits mammalian target of rapamycin (mTOR) signaling. In normal rat kidneys, sestrin 2 was selectively expressed in parietal epithelial cells (PECs), identified by the
Shu Wang et al.
Molecular cancer therapeutics, 14(4), 877-888 (2015-01-24)
We previously reported that a pan-PAD inhibitor, YW3-56, activates p53 target genes to inhibit cancer growth. However, the p53-independent anticancer activity and molecular mechanisms of YW3-56 remain largely elusive. Here, gene expression analyses found that ATF4 target genes involved in

Global Trade Item Number

SKUGTIN
EMU050341-20UG04061831347791
EMU050341-50UG04061828284597