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EMU072781

MISSION® esiRNA

targeting mouse Atg12

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324
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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGCCTCGGAACAGTTGTTTATTTATGTGAATCAGTCCTTTGCCCCTTCCCCAGACCAAGAAGTTGGAACTCTATATGAGTGTTTTGGCAGTGATGGTAAACTGGTCCTGCATTACTGCAAATCCCAGGCATGGGGATGAGCCAGAAATGAACAACTTGATATTTTCACAGAAGAAAAAAAATCAGAGACATTTCGGTGCTGTGGGAAGAGACTTACTATCAAATATTCAGCATGAATCTGTTAGGACCTGTGTTTATGTATAAGAAAACATCATAGAGTATATAGACTAATGAATGAGATTTGTGTCACCATAAAATCATCATGAGAGATTGACGTTAGAGTGTGCCATTACTCCCACACACTCCTGTTCCAGGTCACGTTAGAAAGGAGACTGAAGTTGTATGTGGATTGCAGGTCTCAGGATGACTGAAGGCA

Ensembl | mouse accession no.

ENSMUSG00000032905

NCBI accession no.

NM_026217

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... ATG12(67526), Atg12(67526)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

12 - Non Combustible Liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Sun-Jung Cho et al.
Autophagy, 11(1), 100-112 (2014-12-09)
Autophagy is one of the main mechanisms in the pathophysiology of neurodegenerative disease. The accumulation of autophagic vacuoles (AVs) in affected neurons is responsible for amyloid-β (Aβ) production. Previously, we reported that SUMO1 (small ubiquitin-like modifier 1) increases Aβ levels.

Global Trade Item Number

SKUGTIN
EMU072781-20UG04061828482047
EMU072781-50UG04061828256754