产品名称
MISSION® esiRNA, targeting mouse Atg12
Gene Information
mouse ... ATG12(67526), Atg12(67526)
description
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product line
MISSION®
form
lyophilized powder
esiRNA cDNA target sequence
GGCCTCGGAACAGTTGTTTATTTATGTGAATCAGTCCTTTGCCCCTTCCCCAGACCAAGAAGTTGGAACTCTATATGAGTGTTTTGGCAGTGATGGTAAACTGGTCCTGCATTACTGCAAATCCCAGGCATGGGGATGAGCCAGAAATGAACAACTTGATATTTTCACAGAAGAAAAAAAATCAGAGACATTTCGGTGCTGTGGGAAGAGACTTACTATCAAATATTCAGCATGAATCTGTTAGGACCTGTGTTTATGTATAAGAAAACATCATAGAGTATATAGACTAATGAATGAGATTTGTGTCACCATAAAATCATCATGAGAGATTGACGTTAGAGTGTGCCATTACTCCCACACACTCCTGTTCCAGGTCACGTTAGAAAGGAGACTGAAGTTGTATGTGGATTGCAGGTCTCAGGATGACTGAAGGCA
Ensembl | mouse accession no.
NCBI accession no.
shipped in
ambient
storage temp.
−20°C
Quality Level
General description
MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
Legal Information
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
12 - Non Combustible Liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Sun-Jung Cho et al.
Autophagy, 11(1), 100-112 (2014-12-09)
Autophagy is one of the main mechanisms in the pathophysiology of neurodegenerative disease. The accumulation of autophagic vacuoles (AVs) in affected neurons is responsible for amyloid-β (Aβ) production. Previously, we reported that SUMO1 (small ubiquitin-like modifier 1) increases Aβ levels.
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