F0537
Fusicoccin from Fusicoccum amygdali
≥85% (HPLC)
Synonym(s):
Fusicoccin A
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About This Item
Empirical Formula (Hill Notation):
C36H56O12
CAS Number:
Molecular Weight:
680.82
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352201
MDL number:
biological source
plant (Fusicoccum amygdali)
Quality Level
assay
≥85% (HPLC)
form
solid
storage temp.
−20°C
SMILES string
COCC1CCC2C(C)C(O)C(OC3OC(COC(C)(C)C=C)C(O)C(OC(C)=O)C3O)C4=C(CC(O)C4(C)C=C12)C(C)COC(C)=O
InChI
1S/C36H56O12/c1-10-35(6,7)45-17-26-30(41)33(46-21(5)38)31(42)34(47-26)48-32-28-24(18(2)15-44-20(4)37)13-27(39)36(28,8)14-25-22(16-43-9)11-12-23(25)19(3)29(32)40/h10,14,18-19,22-23,26-27,29-34,39-42H,1,11-13,15-17H2,2-9H3/b25-14-
InChI key
KXTYBXCEQOANSX-QFEZKATASA-N
Application
Fusicoccin (Fusicoccin A), a diterpene glucoside phytotoxin, is used to study 14-3-3-dependent processes such as the activation of H+-ATPase in plants and other client proteins with mode III binding motifs. Fusicoccin is an inducer of a catalase inhibitor that leads to oxidative damage in plants.
Other Notes
A diterpene glucoside with numerous physiological effects on plants.
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Tomonobu Toyomasu
Bioscience, biotechnology, and biochemistry, 72(5), 1168-1175 (2008-05-08)
Cyclic diterpenoids are commonly biosynthesized from geranylgeranyl diphosphate (GGDP) through the formation of carbon skeletons by specific cyclases and subsequent chemical modifications, such as oxidation, reduction, methylation, and glucosidation. A variety of diterpenoids are produced in higher plants and fungi.
Ingrid J de Vries-van Leeuwen et al.
Cancer letters, 293(2), 198-206 (2010-02-16)
Active small molecules have a high potential for the development into new anti-cancer drugs. Here we analysed the effect of the natural occurring fusicoccanes, Fusicoccin-A (FC), Ophiobolin-A (OPH-A) and Ophiobolin-I (OPH-I) on various tumor cell lines. Both FC and OPH-A
Yusuke Ono et al.
Journal of the American Chemical Society, 133(8), 2548-2555 (2011-02-09)
Fusicoccin A and cotylenin A are structurally related diterpene glucosides and show a phytohormone-like activity. However, only cotylenin A induces the differentiation of human myeloid leukemia cells. Since the cotylenin A producer lost its ability to proliferate during preservation, a
Global Trade Item Number
| SKU | GTIN |
|---|---|
| F0537-250UG | 04061832389424 |
| F0537-1MG | 04061826059258 |