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F1058

FSL-Fluorescein

Name: FSL-Fluorescein
Brand: SIGMA

Synonym(s):

FSL-FLRO4(fluorescein)-SA2-L1

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About This Item

Empirical Formula (Hill Notation):

C₇₃H₁₀₉N₄O₁₅PS

Molecular Weight:

1345.70

UNSPSC Code:

41116100

PubChem Substance ID:

329799672

NACRES:

NA.32

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Quality Level

200

storage temp.

−20°C

SMILES string

CCCCCCCC\C=C/CCCCCCCC(=O)OCC(COP(O)(=O)OCCNC(=O)CCCCC(=O)NCCCCCNC(=S)Nc1ccc2c(c1)C(=O)OC23c4ccc(O)cc4Oc5cc(O)ccc35)OC(=O)CCCCCCC\C=C/CCCCCCCC

InChI

1S/C73H109N4O15PS/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-32-40-69(82)87-55-60(90-70(83)41-33-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2)56-89-93(85,86)88-51-50-75-68(81)39-35-34-38-67(80)74-48-36-31-37-49-76-72(94)77-57-42-45-62-61(52-57)71(84)92-73(62)63-46-43-58(78)53-65(63)91-66-54-59(79)44-47-64(66)73/h17-20,42-47,52-54,60,78-79H,3-16,21-41,48-51,55-56H2,1-2H3,(H,74,80)(H,75,81)(H,85,86)(H2,76,77,94)/b19-17-,20-18-

InChI key

OZXSVOLFZKVFHP-CLFAGFIQSA-N

Related Categories

Chemistry & Biochemicals

Biochemicals

Metabolite Libraries

Application

FSL Constructs Video Protocol

All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. Cells modified with FSL constructs are known as kodecytesand usually maintain their normal vitality and functionality. FSL-fluorescein has been specifically designed to create fluorescein-labeled live cells (kodecytes) but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces. Fluorescein-labeled kodecytes can be visualized at the approximate absorbance wavelength of 488 nm and emission at 518 nm.

All FSL constructs disperse in biocompatible media and spontaneously and stably incorporate into cell membranes. FSL-fluorescein has been specifically designed to create fluorescein-labeled live cells (kodecytes) but can also be used to modify other hydrophobic surfaces including fixed cells, virions, and solid phase surfaces.

Other Notes

FSL-fluorescein is a KODE^™ technology construct designed to label hydrophobic surfaces including living cells with biotin. All FSL constructs consist of three essential designable features:

functional component (F)
spacer (S)
diacyl lipid (L)

FSL-fluorescein is comprised of a fluorescein residue representing F, conjugated via a spacer (SA2) to an an activated adipate derivative of dioleoylphosphatidylethanolamine (L1).

Packaged as 1 mg FSL-Fluorescein with 0.42 mg sodium bicarbonate to improve solubility.

Legal Information

KODE Constructs are supplied by KODE Biotech Materials Limited under license from KODE Biotech Limited.

KODE is a trademark of KODE Biotech Ltd.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Visualizing Oncolytic Virus-Host Interactions in Live Mice Using Intravital Microscopy.

Victor Naumenko et al.

Molecular therapy oncolytics, 10, 14-27 (2018-08-04)

Oncolytic virus (OV) therapy is an emerging cancer treatment that uses replicating viruses to infect and kill tumor cells and incite anticancer immunity. While the approach shows promise, it currently fails most patients, indicating strategies to improve OV activity are

Global Trade Item Number

SKU	GTIN
F1058-1MG	04061826703236

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