F5053
Flavin-Containing Monooxygenase-3, Microsomes human
recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution
Synonym(s):
FMO-3
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recombinant
expressed in baculovirus infected insect cells
Quality Segment
form
buffered aqueous solution
mol wt
55-60 kDa
packaging
vial of 2.5 mg
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... FMO3(2328)
General description
Flavin-Containing Monooxygenase-3 (FMO3) is a member of the flavin-containing monooxygenase (FMO) family of enzymes. It is highly expressed in the human liver.
Application
FMO3 is the major human hepatic form.
Biochem/physiol Actions
Flavin-Containing Monooxygenase-3 (FMO3) facilitates the oxidization of several drugs, chemicals, and xenobiotics. Human FMO3 is also involved in the synthesis of N-oxide of trimethylamine (TMAO) from trimethylamine (TMA). Mutations in the FMO3 gene are associated with trimethylaminuria or fish odor syndrome. Deficiency of the FMO3 gene results in lower plasma TMAO levels, which may reduce the risk of developing atherosclerosis and thrombosis.
Physical form
Solution in 100 mM potassium phosphate buffer, pH 7.4
Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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