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Merck
CN

F5178

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

Synonym(s):

FMO-5

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About This Item

EC Number:
NACRES:
NA.54
UNSPSC Code:
12352204
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Product Name

Flavin-Containing Monooxygenase-5, Microsomes human, recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

recombinant

expressed in baculovirus infected insect cells

form

buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

specific activity

≥700 units/mg protein

mol wt

55-60 kDa

packaging

vial of 2.5 mg

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Quality Level

Gene Information

human ... FMO5(2330)

Application

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Biochem/physiol Actions

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Other Notes

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

Physical form

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Storage Class

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Regulatory Information

常规特殊物品
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