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Merck
CN

F5384

Anti-Human IgM (μ-chain specific)−FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Goat Anti-Human IgM (μ-chain specific)−Fluorescein isothiocyanate

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
MFCD00162462

Key Documents

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Product Name

Anti-Human IgM (μ-chain specific)−FITC antibody produced in goat, affinity isolated antibody, buffered aqueous solution

biological source

goat

conjugate

FITC conjugate

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

technique(s)

direct immunofluorescence: 1:32

storage temp.

2-8°C

target post-translational modification

unmodified

Quality Level

300

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Application

Anti-Human IgM (μ-chain specific)-FITC antibody produced in goat was used as secondary antibody in serodiagnosis of Lyme disease based on seroreactivity against Borrelia spirochaetes.

Biochem/physiol Actions

IgM antibodies are present as pentamers in the serum and are produced in response to antigens.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

The product binds human IgM; but does not bind other human Igs.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

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Storage Class

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

常规特殊物品
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Certificates of Analysis (COA)

Lot/Batch Number
0000507131
0000507131
0000443891
0000443891
0000406293

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Nayoung Ko et al.
Scientific reports, 12(1), 9611-9611 (2022-06-11)
Pig-to-human organ transplantation is a feasible solution to resolve the shortage of organ donors for patients that wait for transplantation. To overcome immunological rejection, which is the main hurdle in pig-to-human xenotransplantation, various engineered transgenic pigs have been developed. Ablation
Jingtao Cui et al.
PloS one, 13(11), e0206995-e0206995 (2018-11-08)
Chlamydia pneumoniae (C. pneumoniae) is an obligate intracellular bacterium and a human pathogen that causes respiratory infectious diseases. More than 50% of the adult population worldwide was once infected with C. pneumoniae, but investigations into this topic are insufficient in
First detection and molecular identification of Borrelia garinii isolated from human skin in Taiwan.
Li-Lian Chao et al.
Journal of medical microbiology, 59(Pt 2), 254-257 (2009-11-17)
J C Magee et al.
The Journal of clinical investigation, 96(5), 2404-2412 (1995-11-01)
Immunoglobulins regulate the complement system by activating complement on foreign surfaces and diverting reactive complement proteins away from autologous cell surfaces. Based on this model, we explored the ability of Ig to balance complement activation versus control in a pig-to-primate
Julia Hennicke et al.
New biotechnology, 50, 20-26 (2019-01-11)
IgM antibodies are arousing considerable interest as biopharmaceuticals. Despite their immunotherapeutic potential, little is known about the impact of environmental conditions on product quantity and quality of these complex molecules. Process conditions influence the critical quality attributes (CQAs) of therapeutic
View All Related Papers

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Data Sheet - F5384

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