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Merck
CN

F5551

Hemagglutinin, Filamentous

from Bordetella pertussis, lyophilized powder

Synonym(s):

Anti-HA, FHA, Hemagglutinin, Fimbrial

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Form:
lyophilized powder
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Product Name

Hemagglutinin, Filamentous from Bordetella pertussis, lyophilized powder

form

lyophilized powder

Quality Segment

mol wt

200-220 kDa

shipped in

wet ice

storage temp.

2-8°C

General description

Filamentous Hemagglutinin (FHA) from Bordetella pertussis is a major virulence-associated adhesion factor secreted by these bacteria. It contains an arginine-glycine-aspartate (RGD) sequence. FHA is a derivative of its precursor FhaB.

Biochem/physiol Actions

Filamentous Hemagglutinin (FHA) from Bordetella pertussis enables the attachment of bacteria to the epithelium of the upper respiratory tract. The arginine-glycine-aspartate (RGD) sequence mediates the binding of FHA to sulfated polysaccharides and pulmonary macrophage integrins.

Physical form

lyophilized from 0.05 M Tris HCL, pH 8, with 0.5 M sodium chloride and 5% sucrose


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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