F5557
Fasentin
≥98% (HPLC)
Synonym(s):
N-[4-Chloro-3-(trifluoromethyl)phenyl]-3-oxobutanamide
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About This Item
Empirical Formula (Hill Notation):
C11H9ClF3NO2
CAS Number:
Molecular Weight:
279.64
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: >10 mg/mL
storage temp.
room temp
SMILES string
CC(=O)CC(=O)Nc1ccc(Cl)c(c1)C(F)(F)F
InChI
1S/C11H9ClF3NO2/c1-6(17)4-10(18)16-7-2-3-9(12)8(5-7)11(13,14)15/h2-3,5H,4H2,1H3,(H,16,18)
InChI key
GNYIJZMBLZXJEJ-UHFFFAOYSA-N
Application
Biochem/physiol Actions
Fasentin is a novel inhibitor of glucose uptake, GluT1 inhibitor. Fasentin is a novel inhibitor of glucose uptake that sensitizes cells to FAS-induced cell death. Fasentin selectively sensitized to death ligands, but did not decrease FLIP expression. It alters expression of genes associated with nutrient and glucose deprivation. Fasentin interacted with a unique site in the intracellular channel of the glucose transport protein GLUT1.
Fastentin is a novel inhibitor of glucose uptake, GluT1 inhibitor.
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Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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