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Merck
CN

F5804

Anti-FBG3 (FBXO44) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym(s):

Anti-F Box 3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
Conjugate:
unconjugated
Clone:
polyclonal
Application:
WB
Citations:
4
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biological source

rabbit

Quality Segment

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen ~30 kDa by calculation

species reactivity

human

technique(s)

western blot: 1:500-1:1,000

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... FBXO44(93611)
mouse ... Fbxo44(230903)
rat ... Fbxo44(500587)

Immunogen

peptide corresponding to the human FBG3 protein (amino acids 103-119). This sequence has 94% homology with mouse and rat.

Application

Anti-FBG3 (FBXO44) antibody is suitable for western blot: 1:500-1:1,000.

Biochem/physiol Actions

F-box protein, is the critical component of conserved ubiquitin–protein ligase complex SCF (Skp1/Cdc53-Cullin1/F-box) and acts as a substrate recognition component of the ubiquitin ligase complex SCF (Skp-Cullin-F-box). It is expressed in human tissues including kidney, liver, brain and muscle tissues. It is associated with various critical biological processes such as in regulating the cell cycle, immune response, signaling cascades and developmental programs. The proteins have a bipartite structure and the core complex, whereas divergent protein-protein interaction motifs selectively bind their cognate substrates.

Physical form

Solution of 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.


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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable



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