F7001
5-Fluorotryptamine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C10H11FN2 · HCl
CAS Number:
Molecular Weight:
214.67
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352116
EC Number:
220-307-5
MDL number:
InChI key
YZAWADGJXKCLTI-UHFFFAOYSA-N
InChI
1S/C10H11FN2.ClH/c11-8-1-2-10-9(5-8)7(3-4-12)6-13-10;/h1-2,5-6,13H,3-4,12H2;1H
SMILES string
Cl.NCCc1c[nH]c2ccc(F)cc12
storage temp.
−20°C
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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J Sastre Toraño et al.
Biomedical chromatography : BMC, 14(5), 306-310 (2000-08-29)
A validated new and precise reversed-phase high-performance liquid chromatographic method for the determination of melatonin in human plasma and cerebrospinal fluid, with 5-fluorotryptamine as internal standard, is described. Liquid-liquid extraction with dichloromethane was performed under alkaline conditions. After evaporation of
Thrombin: active-site topography.
L J Berliner et al.
Annals of the New York Academy of Sciences, 485, 80-95 (1986-01-01)
P A Mirau et al.
Biochemistry, 21(4), 615-620 (1982-02-16)
Fluorine-19 nuclear magnetic resonance (19F NMR), optical absorption, and fluorescence spectroscopy have been used to study the interaction of 5-fluorotryptamine (5FTA) with polynucleotides as a model for protein--nucleic acid interactions. In the presence of DNA, denatured DNA, poly(A), and poly(A).poly(U)
E A Tembe et al.
Parasitology, 106 ( Pt 1), 67-73 (1993-01-01)
5-HT is a candidate for the excitatory transmitter at the neuromuscular junction in trematodes including Fasciola hepatica. This study has determined the response of a muscle strip preparation from Fasciola hepatica to 5-HT and a range of agonists that distinguish
Kiowa S Bower et al.
European journal of pharmacology, 580(3), 291-297 (2007-12-18)
Antagonists, but not agonists, of the 5-HT3 receptor are useful therapeutic agents, and it is possible that partial agonists may also be potentially useful in the clinic. Here we show that 5-fluorotryptamine (5-FT) is a partial agonist at both 5-HT3A
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