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F7001

5-Fluorotryptamine hydrochloride

Name: 5-Fluorotryptamine hydrochloride
Brand: SIGMA

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About This Item

Empirical Formula (Hill Notation):

C₁₀H₁₁FN₂ · HCl

CAS Number:

2711-58-2

Molecular Weight:

214.67

NACRES:

NA.32

PubChem Substance ID:

24894924

UNSPSC Code:

12352116

EC Number:

220-307-5

MDL number:

MFCD00051081

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storage temp.

−20°C

SMILES string

Cl.NCCc1c[nH]c2ccc(F)cc12

InChI

1S/C10H11FN2.ClH/c11-8-1-2-10-9(5-8)7(3-4-12)6-13-10;/h1-2,5-6,13H,3-4,12H2;1H

InChI key

YZAWADGJXKCLTI-UHFFFAOYSA-N

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Thrombin: active-site topography.

L J Berliner et al.

Annals of the New York Academy of Sciences, 485, 80-95 (1986-01-01)

Quantitative determination of melatonin in human plasma and cerebrospinal fluid with high-performance liquid chromatography and fluorescence detection.

J Sastre Toraño et al.

Biomedical chromatography : BMC, 14(5), 306-310 (2000-08-29)

A validated new and precise reversed-phase high-performance liquid chromatographic method for the determination of melatonin in human plasma and cerebrospinal fluid, with 5-fluorotryptamine as internal standard, is described. Liquid-liquid extraction with dichloromethane was performed under alkaline conditions. After evaporation of

Pharmacological profile of the 5-hydroxytryptamine receptor of Fasciola hepatica body wall muscle.

E A Tembe et al.

Parasitology, 106 ( Pt 1), 67-73 (1993-01-01)

5-HT is a candidate for the excitatory transmitter at the neuromuscular junction in trematodes including Fasciola hepatica. This study has determined the response of a muscle strip preparation from Fasciola hepatica to 5-HT and a range of agonists that distinguish

Binding of 5-fluorotryptamine to polynucleotides as a model for protein-nucleic acid interactions: fluorine-19 nuclear magnetic resonance, absorption, and fluorescence studies.

P A Mirau et al.

Biochemistry, 21(4), 615-620 (1982-02-16)

Fluorine-19 nuclear magnetic resonance (19F NMR), optical absorption, and fluorescence spectroscopy have been used to study the interaction of 5-fluorotryptamine (5FTA) with polynucleotides as a model for protein--nucleic acid interactions. In the presence of DNA, denatured DNA, poly(A), and poly(A).poly(U)

5-Fluorotryptamine is a partial agonist at 5-HT3 receptors, and reveals that size and electronegativity at the 5 position of tryptamine are critical for efficient receptor function.

Kiowa S Bower et al.

European journal of pharmacology, 580(3), 291-297 (2007-12-18)

Antagonists, but not agonists, of the 5-HT3 receptor are useful therapeutic agents, and it is possible that partial agonists may also be potentially useful in the clinic. Here we show that 5-fluorotryptamine (5-FT) is a partial agonist at both 5-HT3A

Global Trade Item Number

SKU	GTIN
F7001-250MG	04061833284834
F7001-500MG	04061832534725

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