F8307
FR-900098 monosodium salt
≥97% (NMR)
Synonym(s):
(3-(Acetylhydroxyamino)propyl)-phosphonic acid, BRN 2096083, P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid
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About This Item
Empirical Formula (Hill Notation):
C5H11NNaO5P
CAS Number:
Molecular Weight:
219.11
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
MDL number:
InChI key
LCFXFDGYDKNWMD-UHFFFAOYSA-M
SMILES string
[Na+].CC(=O)N(O)CCCP(O)([O-])=O
InChI
1S/C5H12NO5P.Na/c1-5(7)6(8)3-2-4-12(9,10)11;/h8H,2-4H2,1H3,(H2,9,10,11);/q;+1/p-1
assay
≥97% (NMR)
form
powder
storage condition
desiccated, protect from light
color
white to light brown
solubility
H2O: ≥20 mg/mL
storage temp.
−20°C
Quality Level
Related Categories
Biochem/physiol Actions
1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice.
1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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