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F9677

Felodipine

L-type calcium channel blocker, solid

Synonym(s):

4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester, Plendil

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About This Item

Empirical Formula (Hill Notation):
C18H19NO4Cl2
CAS Number:
72509-76-3
Molecular Weight:
384.25
UNSPSC Code:
12352200
PubChem Substance ID:
24278449
NACRES:
NA.77
MDL number:
MFCD00868316
Form:
solid
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Product Name

Felodipine, solid

form

solid

Quality Segment

200

solubility

DMSO: 20 mg/mL, H2O: insoluble

originator

AstraZeneca

SMILES string

CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(Cl)c2Cl)C(=O)OC

InChI

1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3

InChI key

RZTAMFZIAATZDJ-UHFFFAOYSA-N

Gene Information

human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), CACNA2D1(781), NR3C2(4306)

General description

Felodipine is a dihydropyridine derivative. It has diuretic properties. Felodipine has high vascular selectivity. It is used to treat hypertension. Felodipine regulates chronic stable angina.

Biochem/physiol Actions

L-type calcium channel blocker

Features and Benefits

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Warning

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Inhalation

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

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