Skip to Content
Merck
CN

F9926

FIM-1

≥99% purity (TLC), powder

Synonym(s):

N-[3-(3-[2,5-Dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl)propyl]-3′,6′-dihydroxy-3-oxospiro[isobenzofuran-1[3H],9′-[9H]xanthene]-5-carboxamide

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C45H31N4O8
CAS Number:
220518-50-3
Molecular Weight:
755.75
UNSPSC Code:
12171500
PubChem Substance ID:
329799791
NACRES:
NA.47
MDL number:
MFCD03453075

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

Product Name

FIM-1,

SMILES string

Cn1c(cc2ccccc12)C3=C(C(=O)NC3=O)c4cn(CCCNC(=O)c5ccc6c(c5)C(=O)OC67c8ccc(O)cc8Oc9cc(O)ccc79)c%10ccccc4%10

InChI

1S/C45H32N4O8/c1-48-34-9-4-2-7-24(34)20-36(48)40-39(42(53)47-43(40)54)30-23-49(35-10-5-3-8-28(30)35)18-6-17-46-41(52)25-11-14-31-29(19-25)44(55)57-45(31)32-15-12-26(50)21-37(32)56-38-22-27(51)13-16-33(38)45/h2-5,7-16,19-23,50-51H,6,17-18H2,1H3,(H,46,52)(H,47,53,54)

InChI key

WZJAWTNAOLZZOO-UHFFFAOYSA-N

assay

≥99% (TLC)

form

powder

color

red

solubility

DMSO or DMF: soluble

εmax

81.8 at 486 nm in methanol

application(s)

diagnostic assay manufacturing
hematology
histology

shipped in

dry ice

storage temp.

−20°C

Quality Level

200

Related Categories

Biochem/physiol Actions

A fluorescent conjugate of bisindolylmaleimide that specifically binds phosphokinase C at the active site. Can monitor enzyme activation and translocation. This reagent is not membrane permeable. The diacetate form (Sigma No. F9801) is membrane permeable.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
086K1457
071K1690
103K1455

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Maria Rodriguez-Fernandez et al.
BMC bioinformatics, 7, 483-483 (2006-11-04)
We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-modality of many of these problems, traditional local methods usually fail (unless initialized with very good guesses of
Meysam Hashemi et al.
Neuroinformatics, 16(2), 231-251 (2018-03-09)
Mathematical modeling is a powerful tool that enables researchers to describe the experimentally observed dynamics of complex systems. Starting with a robust model including model parameters, it is necessary to choose an appropriate set of model parameters to reproduce experimental
Hossein Jashnsaz et al.
iScience, 23(10), 101565-101565 (2020-10-22)
Computationally understanding the molecular mechanisms that give rise to cell signaling responses upon different environmental, chemical, and genetic perturbations is a long-standing challenge that requires models that fit and predict quantitative responses for new biological conditions. Overcoming this challenge depends

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service