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Merck
CN

G211230

DMT-2′Fluoro-dG(ib) Phosphoramidite

configured for ABI

Synonym(s):

DMT-2′Fluoro-dG(ib) Amidite

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About This Item

Empirical Formula (Hill Notation):
C44H53FN7O8P
CAS Number:
Molecular Weight:
857.91
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
41116105
MDL number:
Assay:
≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)
Biological source:
non-animal source (no BSE/TSE risk)
Form:
powder
Storage temp.:
−20°C
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biological source

non-animal source (no BSE/TSE risk)

Quality Segment

product line

Proligo Reagents

assay

≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)

form

powder

technique(s)

oligo synthesis: suitable

impurities

≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.5% single Impurity (reversed phase HPLC), ≤3% residual Solvent content

color

white to off-white

λ

conforms (UV/VIS Identity)

suitability

conforms to structure for H-NMR, conforms to structure for LC-MS

compatibility

configured for ABI

nucleoside profile

base: deoxyguanosine
base protecting group: isobutyryl
2' protecting group: fluoro
5' protecting group: DMT
deprotection: fast/standard

storage temp.

−20°C

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](F)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4C(=O)NC(NC(=O)C(C)C)=Nc34)(c5ccccc5)c6ccc(OC)cc6

InChI

1S/C44H53FN7O8P/c1-27(2)40(53)49-43-48-39-37(41(54)50-43)47-26-51(39)42-36(45)38(60-61(58-24-12-23-46)52(28(3)4)29(5)6)35(59-42)25-57-44(30-13-10-9-11-14-30,31-15-19-33(55-7)20-16-31)32-17-21-34(56-8)22-18-32/h9-11,13-22,26-29,35-36,38,42H,12,24-25H2,1-8H3,(H2,48,49,50,53,54)/t35-,36-,38-,42-,61?/m1/s1

InChI key

KJFUMXZZVYMQEU-AOCJBPQJSA-N



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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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