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G2785

Glycitein

≥97% (HPLC), synthetic (organic), powder

Synonym(s):

4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein

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About This Item

Empirical Formula (Hill Notation):
C16H12O5
CAS Number:
40957-83-3
Molecular Weight:
284.26
UNSPSC Code:
41106305
PubChem Substance ID:
329799906
NACRES:
NA.51
MDL number:
MFCD00016679
Assay:
≥97% (HPLC)
Biological source:
synthetic (organic)
Form:
powder
Solubility:
DMF: 1 mg/mL, clear, colorless to faintly yellow
Storage temp.:
−20°C
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Product Name

Glycitein, ≥97% (HPLC)

biological source

synthetic (organic)

Quality Segment

assay

≥97% (HPLC)

form

powder

solubility

DMF: 1 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

COc1cc2C(=O)C(=COc2cc1O)c3ccc(O)cc3

InChI

1S/C16H12O5/c1-20-15-6-11-14(7-13(15)18)21-8-12(16(11)19)9-2-4-10(17)5-3-9/h2-8,17-18H,1H3

InChI key

DXYUAIFZCFRPTH-UHFFFAOYSA-N

Application

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Biochem/physiol Actions

Glycitein possesses weak estrogenic activity than other soy isoflavones.
Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Eyeshields, Gloves, type N95 (US)

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